Electroconvulsive Therapy in Severe Depression: Is Amnesia a Problem?

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Electroconvulsive Therapy in Severe Depression: Is Amnesia a Problem?

Introduction: Depression is the leading global cause of disability and approximately, 350 million people suffer from depression worldwide. Despite the availability of numerous psychopharmacological treatments, evidence indicates that only 60–70% of persons who tolerate antidepressants will respond to first-line drug therapy for major depressive disorder. Resistance to the antidepressant medicat...

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Dexamethasone in electroconvulsive therapy: efficacy for depression and post-ECT amnesia.

Dexamethasone, compared to placebo in a double-blind study, failed to prevent the memory deficiency that typically accompanies electroconvulsive therapy (ECT) (n = 48 patients treated for DSM-III diagnosed major depressive disorder). Rather, the administration of the drug was associated with attention (p less than 0.02) and short-term memory (p less than 0.0003) difficulties in both bilateral a...

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Retrograde amnesia after electroconvulsive therapy: a temporary effect?

OBJECTIVE Although electroconvulsive therapy (ECT) is generally considered effective against depression, it remains controversial because of its association with retrograde memory loss. Here, we assessed memory after ECT in circumstances most likely to yield strong retrograde amnesia. METHOD A cohort of patients undergoing ECT for major depression was tested before and after ECT, and again at...

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Neurophysiological Characteristics of Magnetic Seizure Therapy vs. Electroconvulsive Therapy in Geriatric Patients with Severe Depression

Objective: Magnetic seizure therapy (MST) is under development as an alternative to electroconvulsive therapy (ECT), as it offers reduction in depression symptoms with fewer adverse cognitive effects. This study examined the feasibility and efficacy of MST versus ECT in a randomized trial of geriatric patients with severe depression, then compared the neurophysiological characteristics of seizu...

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Ultrasonic antidepressant therapy might be more effective than electroconvulsive therapy (ECT) in treating severe depression.

ECT is widely acknowledged as an effective treatment for severe depression (I), but its drawbacks of entailing a seizure, general anesthesia, post-ictal confusion and memory disturbance can be problematical to the extent of preventing some patients from undergoing the treatments often enough to sustain relief. According to Higgins et al (2), stimulation of specific points on the surface of the ...

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ژورنال

عنوان ژورنال: IOSR Journal of Dental and Medical Sciences

سال: 2017

ISSN: 2279-0861,2279-0853

DOI: 10.9790/0853-1605127177